这篇研究说明了适当增加物理压力对我们人体各个组织所带来的好处，而我们可以利用适当的运动让我们的身体来承受这些压力，进而强化这些组织，避免萎缩或伤害。
| Organ System | Tissue/Organ | Stress/Activity Level High |
| Musculoskeletal | Bone | ↑BMD ↑strength |
| Muscle | ↑contractile protein ↑fiber diameter f peak tension ↑peak power |
|
| Tendon | ↑CSA ↑stiffness ↑strength |
|
| Ligament | ↑CSA ↑stiffness ↑strength |
|
| Cartilage | ↑proteoglycan content ↑cartilage thickness ↑stiffness |
|
| Integumentary | Skin | ↑collagen content ↑collagen fiber diameter ↑skin thickness ↑strength |
| Cardiopulmonary/vascular | Heart | ↑cardiac muscle mass ↑capillary density ↑stroke volume ↓metabolic capacity |
| Blood vessels | ↑vascular diameter ↑arterial compliance |
|
| Neuromuscular | Neurons | ↑maximum discharge rate ↓recruitment threshold ↑activation during MVC neurogenesis (hippocampus) ↑motor unit synchronization ↑dendritic arborization ↑serotonergic neural activity ↑synaptic transmission |
https://academic.oup.com/ptj/article/82/4/383/2837004